Periwell
Category: MoodClinical Profile

Mood Swings

Rapid, unpredictable shifts between weeping, rage, and sudden calm.

Biological Mechanism

The erratic, saw-tooth hormone profile of perimenopause (particularly high estrogen 'spikes' followed by massive drops) rapidly alters serotonin and dopamine receptor sensitivity.

Common Misdiagnoses

Bipolar Disorder, Borderline Personality Disorder

Evidence-Based Treatments

  • 01Cycle suppression

    Using continuous contraception or HRT to flat-line the ovarian fluctuations.