The HRT Evidence Hub
Independent, post-WHI clinical evidence for Hormone Replacement Therapy types, routes of administration, and symptom efficacies.
HRT Delivery Methods
Transdermal Estradiol (Patch)
→Estrogen
Reduces hot flash frequency and severity by 75-80%
Transdermal Estradiol (Gel)
→Estrogen
Equivalent efficacy to patch for hot flashes
Oral Micronized Progesterone
→Progestogen
Essential endometrial protection
Levonorgestrel IUD
→Progestogen
Reduces heavy menstrual bleeding by up to 90%