Periwell
Method: Estrogen

Transdermal Estradiol (Gel)

+Clinical Pros

  • ✓ Equivalent efficacy to patch for hot flashes
  • ✓ Prevents bone loss
  • ✓ Easy to adjust dose (pump titration)
  • ✓ Zero increased clot risk

-Clinical Cons

  • ✕ Must wait for it to dry (3-5 minutes)
  • ✕ Transference risk to children/pets if not covered
  • ✕ Requires daily compliance

Is Transdermal Estradiol (Gel) working for you?

HRT takes 3-6 months to fully regulate receptors. Track your baseline symptoms in Periwell before starting, and measure the delta precisely.

Track Efficacy in Periwell