Periwell
Category: Skin & HairClinical Profile

Dry Skin

Skin becoming papery thin, intensely itchy, or stubbornly dry despite heavy moisturizers.

Biological Mechanism

Estrogen stimulates collagen production, hyaluronic acid synthesis, and sebum (oil) production. When estrogen drops, the skin literally loses its ability to hold water and its structural matrix breaks down. The intense itching (formication) feels like ants crawling under the skin.

Common Misdiagnoses

Eczema, Allergies, Scabies (if formication is severe)

Evidence-Based Treatments

  • 01HRT

    Maintains dermal thickness and hydration if started early.

  • 02Ceramide-rich moisturizers

    Necessary to repair the compromised skin barrier.