Category: MusculoskeletalClinical Profile
Bone Density Loss
The silent acceleration of bone remodeling that begins well before your final period.
Biological Mechanism
Estrogen restrains osteoclasts (the cells that break down bone). As estrogen declines in perimenopause, the brakes come off bone resorption. Up to 10% of a woman's total bone mass can be lost during the transition alone, long before clinical menopause.
Common Misdiagnoses
Normal aging, Assumed normal until a fracture occurs
Evidence-Based Treatments
- 01HRT
The most effective intervention for preventing menopausal bone loss if started early.
- 02Resistance training
Heavy lifting stimulates osteoblast activity.