Periwell
Evidence Level: Limited

Maca Root

Lepidium meyenii

Targeted For:Low LibidoFatigueMood swings

Clinical Trial Results

Small double-blind trials show significant improvement in SSRI-induced sexual dysfunction in women, and mild improvements in postmenopausal sexual dysfunction. High placebo effect noted in studies.

Biological Mechanism

Does not alter circulating estrogen, testosterone, or LH levels. Its mechanism of action for libido enhancement is unknown, possibly relating to its high concentration of unique fatty acids (macamides) acting on the endocannabinoid system.

Known Risks & Side Effects

  • Generally recognized as safe (it is a food crop)
  • Can be stimulating/disturb sleep if taken late in day

Medication Interactions

  • None well-documented

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